1.囊腫病的發(fā)病機(jī)理

2.纖毛在器官發(fā)育和穩(wěn)態(tài)維持中的功能

3.腎臟上皮細(xì)胞分化

代表論文:

Valeria Padovano, Ivana Y. Kuo, Lindsey K. Stavola, Hans R. Aerni, Benjamin J. Flaherty, Hannah C. Chapin, Ming Ma, Stefan Somlo, Alessandra Boletta, Barbara E. Ehrlich, Jesse Rinehart, and Michael J. Caplan. (2017). The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function. Molecular Biology of the Cell. 28(2):261-269.
 
Ming Ma, Anna-Rachel Gallagher, Stefan Somlo. (2017). Ciliary mechanisms of cyst formation in polycystic kidney disease. Cold Spring Harbor Perspectives in Biology. 9(11). pii: a028209. doi: 10.1101/cshperspect.a028209.(封面)(pdf1)
 
Yuanyuan Li, Xin Tian, Ming Ma, Shanshan Kong, Stefan Somlo, Zhaoxia Sun (2016). Deletion of the Joubert syndrome gene Arl13b leads to cystic kidney in mouse. Journal of the American Society of Nephrology. 27(12): 3628-3638.
 
4.Ming Ma, Xin Tian, Peter Igarashi, Gregory J. Pazour, and Stefan Somlo (2013). Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease. Nature Genetics. (Article) 45 (9) 1004-1012. (pdf2)

Ellen F. Carney “Polycystic kidney disease: Cyst growth and cilia in ADPKD” in Nature Review Nephrology. 9, 555 (2013). 突出推薦
Ong A and Streets A: F1000 Prime Recommendation of [Ma M et al., Nat Genet 2013]. In F1000Prime, 30 Sep 2013. 推薦
Patankar JV. Novel cilia-dependent pathway activates rapid cyst growth in autosomal dominant polycystic kidney disease. Clinical Genet. 2014 Mar; 85 (3):230-2. 熱點(diǎn)推薦
5.Hong Ma, Akashi Togawa, Keita Soda, Junhui Zhang, Sik Lee, Ming Ma, Zhiheng Yu, Thomas Ardito, Jan Czyzyk, Lonnette Diggs, Dominique Joly, Shinji Hatakeyama, Eiji Kawahara, Lawrence Holzman, Jun Lin Guan and Shuta Ishibe (2010). Inhibition of podocyte FAK protects against proteinuria and foot process effacement. Journal of the American Society of Nephrology. 21 (7) 1145-1156.

6.Chung-Der Hsiao, May-Su You, Ying-Jey Guh, Ming Ma, Yun-Jin Jiang, Pung-Pung Hwang (2007). A positive regulatory loop between foxi3a and foxi3b is essential for specification and differentiation of zebrafish epidermal ionocytes. PLoS ONE 2:e302.

7.Ming Ma and Yun-Jin Jiang (2007). Jagged2a-Notch signaling mediates cell fate choice in zebrafish pronephric duct. PLoS Genetics. 3(1) e18. (pdf3)

8.Ming Ma, Teck Koon Tan and Sek Man Wong (2003). Identification and molecular phylogeny of Epulorhiza isolates from tropical orchids. Mycological Research. 107: 1041-1049.

實(shí)驗(yàn)室招收對(duì)生物醫(yī)學(xué)領(lǐng)域感興趣的博士后，博士研究生，碩士研究生和本科生。歡迎電郵聯(lián)系，電子郵箱skymaming@swu.edu.cn